[烧伤后应用甘油保存的同种裂厚皮肤的适应证和结果]。

J C Bruck, R Büttemeyer, A Grabosch, A Weyer
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引用次数: 0

摘要

自1983年以来,用甘油保守的同种异体裂厚皮肤移植治疗二度烧伤被发表。针对艾滋病的实际问题,改进了分厚皮肤的收集方法,并创造了一种获得器官供体分厚皮肤的新方法,以防止病毒的转移。由于具有传染性的高安全性,柏林烧伤中心对二度烧伤患者采用同种异体甘油保存的供体皮肤进行皮肤移植进行了标准化。为防止二度烧伤后肉芽组织的形成,在创伤后第三天对坏死髓质切向清创1/10 mm厚的切片,并将1:1.5网状移植物覆盖的缺损延长。将展示1988年和1989年按照这一方案治疗的267名病人的结果。11%的成人同种异体皮肤移植在移植后6个月没有发生排斥反应,2%的病例烧伤深度不能正确估计,肥厚疤痕必须切除并用自体裂厚皮肤覆盖。一般二度烧伤经清创和异体裂厚皮肤覆盖后愈合,无增生性瘢痕形成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Indication for and results of the application of glycerol-preserved homologous split-thickness skin following burns].

Since 1983 the treatment of second-degree burns with glycerol-conserved allogenic split-thickness skin grafts is published. In case of actual problems with AIDS the gathering of split-thickness skin was modified and a new method for gaining split-thickness skin of organ-donors created to prevent the virus transfer. Because of these high security in contagiousness the skin graft transplantation with allogenic glycerol-conserved donor-skin in case of second-degree-burns was standardized in the Berlin Burn Center. To prevent the formation of granulation tissue after second-degree burns a tangential debridement of necrotic corium will be done in 1/10 mm thick slices on the third posttraumatic day and the defects covered with 1:1.5 mesh grafts extended. The results of 267 patients in 1988 and 1989, who were treated in accordance to this regimen, will be demonstrated. In 11% of cases the alloplastic skin graft in adults was not rejected 6 month after transplantation and in 2% of cases the depth of burn was not estimated properly and hypertrophic scars had to be excised and covered with autogenous split-thickness skin. General second-degree-burn healed after debridement and covering with allogeneic split-thickness skin without formation of hypertrophic scars.

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