糖尿病视网膜病变全视网膜光凝术后视网膜神经纤维层厚度的变化

E. Wasfi, Kamel Soliman, R. Mohammed, Ali Ryad
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引用次数: 0

摘要

背景:全视网膜光凝(PRP)是治疗高风险增殖性糖尿病视网膜病变的金标准。目的:应用光学相干断层扫描评价PRP术后视网膜乳头周围神经纤维层厚度的变化。材料与方法:分别于PRP前、PRP后1、3、6个月测定RNFL厚度。结果:prp后1个月,平均乳头周围RNFL厚度较基线显著增加(P = 0.001), prp后3个月,RNFL厚度较基线显著减少(P = 0.1), 6个月时,RNFL厚度较基线显著减少(P = 0.0001)。结论:PRP应谨慎使用,尽量减少注射次数,避免过度损伤视网膜内层。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in retinal nerve fiber layer thickness after panretinal photocoagulation in diabetic retinopathy
Context: Panretinal photocoagulation (PRP) is the gold standard treatment for high risk proliferative diabetic retinopathy. Aim: The evaluation of peripapillary retinal nerve fiber layer (RNFL) thickness changes in eyes undergoing PRP by optical coherence tomography. Materials and Methods: RNFL thickness was measured before PRP, then after PRP by 1, 3, and 6 months, respectively. Results: Mean peripapillary RNFL thickness increased significantly 1 month after P (P = 0.001), then showed insignificant decrease at 3 months' post-PRP (P = 0.1), then it showed significant decrease at 6 months (P = 0.0001) compared to baseline. Conclusions: PRP should be used with a great caution with least number of shots to avoid excessive damage to inner retinal layers.
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