综合手术与全身经皮血管内管理治疗系统性动脉粥样硬化

Hassan Walid, A. Amr, H. Mariam, Saadi Khaldoun Al, E. Sharaf
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引用次数: 0

摘要

一个动脉部位的动脉粥样硬化性疾病,使血管轴内其他部位受影响的概率提高约50%。因此,一旦在一个部位(如冠状动脉疾病(CAD))发现血管病变,就必须彻底评估其他部位(如脑和外周循环),特别是在有多种危险因素的患者中。经皮介入治疗(PCI)是一种保守、合理的治疗方法;有时它取代了手术的选择,特别是随着药物洗脱支架(DES)和联合抗缺血药物的新时代。长期来看,冠状动脉旁路移植术(CABG)比PCI更受青睐,是治疗复杂多支冠状动脉疾病(MVCAD)的经济有效的方法[1]。然而,与CABG相比,DES的成本效益的证据基础越来越多[1]。尽管冠状动脉旁路移植术有诸多益处,但仍有15%至25%的患者在手术后一年内发生移植物关闭[2]。颈动脉粥样硬化性疾病可因栓塞、血栓形成或血流动力学损害而导致缺血性卒中或短暂性脑缺血发作(TIA)[3]。对于明显> 70%的狭窄患者,颈动脉内膜切除术(CEA)是首选和唯一的血运重建方法[3-12],随后引入经导管经皮血管成形术和支架植入术[13-20]。对于选择的颈动脉狭窄70% ~ 99%的患者,如果存在以下情况之一,建议行颈动脉支架(CAS)而非颈动脉内膜切除术(CEA):颈动脉病变不适合手术通路,辐射性狭窄,颈动脉内膜切除术后再狭窄,临床上明显的心脏、肺部或其他疾病,大大增加麻醉和手术的风险[13-24]。我们在此报告一例78岁的严重冠状动脉、颈动脉和外周动脉粥样硬化患者,他展示了手术和支架混合入路在这种情况下的成功解决方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Systemic Atherosclerosis Treated by Hybrid Surgical and Systemic Percutaneous Endovascular Management
Atherosclerotic disease in one arterial site, raise the probability of having other sites affected by about 50% within the vascular axis. Hence once vascular pathology found in one site i.e. coronary artery disease (CAD), other sites i.e. Cerebral and peripheral circulation must be assessed thoroughly, especially in patients with multiple risk factors. Percutaneous intervention (PCI) is a conservative reasonable solution for high risk and inoperable cases; sometimes it supersedes the choice surgery especially with the new era of drug eluting stents (DES) and combined Anti-Ischemic medications. Coronary artery bypass graft (CABG) rather than PCI was the favored cost-effective treatment for complex multivessel coronary artery disease (MVCAD) in the long term [1]. While the evidence base for the cost-effectiveness of DES compared with CABG is growing [1]. Despite the benefits of Coronary Artery Bypass Graft surgery, 15% to 25% of patients develop graft closure within one year following the procedure [2]. Carotid atherosclerotic disease can lead to ischemic stroke or transient ischemic attack (TIA) from embolization, thrombosis, or hemodynamic compromise [3]. Carotid endarterectomy (CEA) was the initial and sole revascularization method for a significant > 70% stenosis [3-12], followed later by introduction of transcatheter Percutaneous angioplasty and stenting [13-20]. For a selected patients with carotid stenosis of 70 to 99 percent, carotid artery stent (CAS) rather than carotid endarterectomy (CEA) is recommended if any of the following conditions are present: A carotid lesion that is not suitable for surgical access, Radiation-induced stenosis, restenosis after CEA, and clinically significant cardiac, pulmonary, or other disease that greatly increases the risk of anesthesia and surgery [13-24]. We hereby present a case of 78-years-old with severe coronary, carotid and peripheral arterial atherosclerosis who showed a successful example of the solution of Hybrid approach of surgical and stenting approach in such cases.
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