局部肿瘤的直流电化学治疗

Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269) Pub Date : 1998-02-15 DOI:10.1109/ICBEM.1998.666374

C. Chou, N. Vora, J.R. Li, W. Wang, Y. Yen, R. Ren, J. McDougall, C. Stand, B. Zhou, L. Weiss

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引用次数: 1

摘要

为了在美国发展癌症电化学治疗(ECT)，我们已经进行了基础研究并开始了I期临床试验。我们的体内初步结果表明ECT对RIF-I小鼠肿瘤和大鼠纤维肉瘤有效。在体外研究中，ECT通过集落形成实验清楚地证明了剂量依赖性的人口腔癌KB细胞生长抑制。我们已经开始了一项动物研究，以解决电痉挛治疗大鼠乳腺癌的方法学问题。同时，我们开始了治疗复发性浅表恶性肿瘤患者的临床试验。我们的目标是使ECT成为治疗局部肿瘤的一种有用的替代方法。

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Electrochemical treatment of localized tumors with direct current

To develop cancer electrochemical treatment (ECT) in the United States, we have conducted basic studies and started a Phase I clinical trial. Our in vivo preliminary results indicate that ECT is effective on RIF-I mouse tumor and rat fibrosarcomas. In the in vitro study ECT clearly demonstrated dose-dependent human oral carcinoma KB cell growth inhibition by colony-forming assay. We have started an animal study to resolve the ECT methodological problems for rat breast cancer. Meanwhile, we began a clinical trial treating patients with recurrent superficial measurable malignant tumors. Our goal is to make ECT a useful alternative method for treating localized tumors.

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Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)

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