用植物生物学的模块化PET系统PhytoPET成像玉米植株

2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC) Pub Date : 2013-11-01 DOI:10.1109/NSSMIC.2013.6829796

S. Lee, B. Kross, J. McKisson, J. McKisson, A. Weisenberger, W. Xi, C. Zorn, G. Bonito, C. Howell, C. Reid, A. Crowell, L. Cumberbatch, C. Topp, M. Smith

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引用次数: 5

摘要

PhytoPET是一种模块化正电子发射断层扫描(PET)系统，专为植物成像而设计。PhytoPET设计允许灵活安排PET探测器，基于单个独立探测器模块，由单个Hamamatsu H8500位置敏感光电倍增管和像素化LYSO阵列构建。我们已经使用PhytoPET系统在杜克大学生物系Phytotron进行了初步的玉米植物成像研究。本文介绍了利用PhytoPET系统对正电子发射示踪剂11C在玉米植株中的生物分布进行成像的初步评价。通过叶片标记试管将11c - co2装载到玉米幼苗中，并通过每侧灵活排列的PhytoPET模块对11c -糖的易位进行成像。PhytoPET系统成功地对玉米植株内的11C进行了成像，并允许动态测量11C-糖从叶片到根的转运。

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Imaging corn plants with PhytoPET, a modular PET system for plant biology

PhytoPET is a modular positron emission tomography (PET) system designed specifically for plant imaging. The PhytoPET design allows flexible arrangements of PET detectors based on individual standalone detector modules built from single Hamamatsu H8500 position sensitive photomultiplier tubes and pixelated LYSO arrays. We have used the PhytoPET system to perform preliminary corn plant imaging studies at the Duke University Biology Department Phytotron. Initial evaluation of the PhytoPET system to image the biodistribution of the positron emitting tracer 11C in corn plants is presented. 11CO2 is loaded into corn seedlings by a leaf-labeling cuvette and translocation of 11C-sugars is imaged by a flexible arrangement of PhytoPET modules on each side. The PhytoPET system successfully images 11C within corn plants and allows for the dynamic measurement of 11C-sugar translocation from the leaf to the roots.

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2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)

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