Dynamic functional network response to visual stimulus in areas of residual vision

When vision is lost in patients with optic nerve damage, partially damaged areas of residual vision (ARV) are found in their visual fields. Here, detection of visual targets is unstable due to cell loss and lack of neuronal synchronization. Because ARVs have the greatest potential for vision recovery and restoration, we described their dynamic brain network reorganization and evaluate how target detection is controlled by rapid functional brain network changes in ARV. Our study sheds light on the inner brain network topology changes during vision cognition in patients and how network integration and segregation features are associated with plasticity of residual vision from a global network perspective.