阿拉伯联合酋长国出生时卡介苗的评价

M.R. Sedaghatian, I.A.K. Shana'a
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引用次数: 30

摘要

387名出生时接受卡介苗接种的健康足月婴儿在接种后6-8周接受结核菌素PPD试验。这些婴儿中有92%在当时有明显的卡介苗疤痕。所有婴儿都接受了PPD测试,但只有264名婴儿返回进行测试。37例(14%)的婴儿结核菌素试验为阴性,另外60例(23%)的婴儿硬化小于5毫米。在不同的国家中也观察到同样的模式。11例接种后无卡介苗瘢痕的婴儿中,3例出现大于5mm硬结的PPD阳性反应。卡介苗瘢痕大小与结核菌素试验硬结有显著相关性;0.001. 接种疫苗的并发症极少。我们在卡介苗接种部位观察到3例无菌脓肿,脓肿自行消退。我们认为现有的疫苗是安全有效的,并且卡介苗疤痕形成和结核菌素转化的比率高于大多数研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of BCG at birth in the United Arab Emirates

A total of 387 healthy full term infants who received BCG vaccination at birth were evaluated by the tuberculin PPD test at 6–8 weeks post vaccination. A total of 92% of these infants had visible BCG scars at that time. All infants were tested with PPD but only 264 returned for the test to be read. The tuberculin test was negative in 37 (14%) and of less than 5 mm induration in another 60 (23%) of the infants.

The same pattern was observed in different nationalities. Of 11 infants with no BCG scar after vaccination, 3 had positive PPD reactions of more than 5 mm induration. There was a significant correlation between the size of the BCG scar and induration of tuberculin test P < 0.001. The complications of the vaccination were minimal. We have observed 3 sterile abscesses at the site of BCG vaccination which resolved spontaneously. We think the available vaccine is safe and potent, and that the rate of BCG scar formation and of tuberculin conversion is higher than in most studies.

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