超长时间除颤的体外研究:无电容除颤器的设计和测试

M. Triventi, E. Mattei, A. Delogu, F. Censi, G. Calcagnini, P. Bartolini, F. Aguel, J. Stohlman, V. Krauthamer
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引用次数: 0

摘要

本文的目的是描述一种允许提供任意波形冲击的除颤器,能量高达10J,持续时间长达100毫秒。此外,还介绍了对离体家兔心脏进行电击的数据。在除颤器的设计与实现中采用的解决方案为:充电电池供电;线性AB级功放桥式输出;模拟和数字线路与PC和接地的光学隔离;测量传递给负载的实际电压、电流和能量。实验室测试表明,除颤器能够提供上升时间小于150 us的冲击,对于非常长的波形(100 ms)也不会倾斜,峰值电流高达10 a。然后将该系统用于兔心脏,以确定一种方案,以研究波形持续时间对除颤阈值的影响。我们证明了实验除颤器产生和传递真正任意波形的可行性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In-vitro investigation of very long defibrillation shocks: Design and testing of a capacitor-free defibrillator
The aim of this paper is to describe a defibrillator that allows the delivery of arbitrary waveform shocks, with energy up to 10J and duration up to 100 ms. In addition, data from shocks delivered to isolated rabbitpsilas hearts are presented. The solutions adopted in the design and realization of the defibrillator were: rechargeable battery power; linear AB class power amplifier output in bridge configuration; optical isolation of analog and digital lines to and from the PC and earth ground; measure of the actual voltage, current and energy delivered to the load. Laboratory testing showed that the defibrillator is capable to deliver shocks with a rising time less than 150 us, no tilting also for very long waveforms (100 ms), peak current up to 10 A. The system was then used on rabbit hearts to define a protocol to investigate the effect of waveform duration on defibrillation threshold. We demonstrate the feasibility of an experimental defibrillator for the generation and delivery of true arbitrary waveforms.
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