{"title":"霍奇金淋巴瘤的病理生理及免疫系统的作用","authors":"Kalsoom Abidi Malik, Zunaira Hameed, Marvah Qiass","doi":"10.26502/ami.93650086","DOIUrl":null,"url":null,"abstract":"Hodgkin’s lymphoma is a disease which originates from white blood cells that are known as lymphocytes. It is primarily mutation of B lymphocytes, it has a special ability to cause deficiency of immune system and also give immune escape process to avoid from self-destruction. In this article we will discuss Hodgkin’s disease and its relation with immune system and also evaluate the function of regulatory B cells in Hodgkin’s disease, origin of HRS and HP cells, role of stains and down regulation of B cells. Epstein-Barr disease (EBV) is the vitally powerful expert that dependably has been connected with HD, EBV-encoded RNA is recognized in the HRS cells more than in 40% of cases.","PeriodicalId":222617,"journal":{"name":"Archives of Microbiology & Immunology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pathophysiology of Hodgkin’s Lymphoma and Role of Immune System\",\"authors\":\"Kalsoom Abidi Malik, Zunaira Hameed, Marvah Qiass\",\"doi\":\"10.26502/ami.93650086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hodgkin’s lymphoma is a disease which originates from white blood cells that are known as lymphocytes. It is primarily mutation of B lymphocytes, it has a special ability to cause deficiency of immune system and also give immune escape process to avoid from self-destruction. In this article we will discuss Hodgkin’s disease and its relation with immune system and also evaluate the function of regulatory B cells in Hodgkin’s disease, origin of HRS and HP cells, role of stains and down regulation of B cells. Epstein-Barr disease (EBV) is the vitally powerful expert that dependably has been connected with HD, EBV-encoded RNA is recognized in the HRS cells more than in 40% of cases.\",\"PeriodicalId\":222617,\"journal\":{\"name\":\"Archives of Microbiology & Immunology\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Microbiology & Immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26502/ami.93650086\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Microbiology & Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26502/ami.93650086","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Pathophysiology of Hodgkin’s Lymphoma and Role of Immune System
Hodgkin’s lymphoma is a disease which originates from white blood cells that are known as lymphocytes. It is primarily mutation of B lymphocytes, it has a special ability to cause deficiency of immune system and also give immune escape process to avoid from self-destruction. In this article we will discuss Hodgkin’s disease and its relation with immune system and also evaluate the function of regulatory B cells in Hodgkin’s disease, origin of HRS and HP cells, role of stains and down regulation of B cells. Epstein-Barr disease (EBV) is the vitally powerful expert that dependably has been connected with HD, EBV-encoded RNA is recognized in the HRS cells more than in 40% of cases.
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