Kawasaki disease -up to date-

Abstract Kawasaki disease (KD) was reported as a novel disease in The Japanese Journal of Allergology in 1967 Although many causative pathogens have been proposed, the cause of KD remains unknown The guidelines for the diagnosis of KD using clinical symptoms were revised in 2019 The purpose of this 6th revision is to focus on the prompt diagnosis for KD for not delaying treatment The treatment for intravenous immunoglobulin-resistant acute KD is important The pathogenesis of KD is vasculitis caused by systemic inflammation in genetically susceptible children During the recent and ongoing coronavirus disease 2019 (COVID-2019) pandemic, the pediatric severe cases showing features similar to KD were reported in Europe and US Further studies will be needed to clarify the involvement of COVID-19 in the pathogenesis of KD