一种简单有效的幼猴尿液采集方法

Journal of pharmacological methods Pub Date : 1990-09-01 DOI:10.1016/0160-5402(90)90021-C

Arturo Lopez-Anaya, Jashvant D. Unadkat, Louise A. Schumann

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引用次数: 4

摘要

在儿科医学中使用的尿布方法已被用于婴儿猕猴(Macaca nemestrina)的全尿收集并验证。该装置由纤维素海绵和聚乙烯片组成。所提出的方法是非侵入性的，简单的，并且不会明显阻碍婴儿的运动。当需要收集全部尿液进行药代动力学研究时，该方法应该是有用的。

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Simple and effective procedure for complete urine collection from infant macaques (Macaca nemestrina)

A diaper method, used in pediatric medicine, has been adapted and validated for total urine collection from infant macaques (Macaca nemestrina). The device consists of cellulose sponges and polyethylene sheets. The method proposed is non-invasive, simple, and does not significantly hinder the movement of the infant. The method should be useful when one is conducting pharmacokinetic studies in which total urine collection is required.

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Journal of pharmacological methods

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