{"title":"吡拉西坦在小儿神经病学中的最新应用。","authors":"Aamir Jalal Al-Mosawi","doi":"10.46940/snnsj.02.1002","DOIUrl":null,"url":null,"abstract":"Abstract Piracetam (2-oxo-1-pyrrolidine acetamide) is a cyclical derivative of GABA (gamma-aminobutyric acid). It was first synthesized during the 1950s by Corneliu E. Giurgea. There are reports of its use for epilepsy in the 1950s. Piracetam can beneficially influence impaired brain function by improving neuronal and cognitive functions without acting as a sedative or stimulant, increasing blood flow and oxygen consumption in the brain and improving the function of the neurotransmitters and brain neurotransmission.","PeriodicalId":280856,"journal":{"name":"SunKrist Neurology, Neurosurgery and Stroke Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Recent Uses of Piracetam in Pediatric Neurology.\",\"authors\":\"Aamir Jalal Al-Mosawi\",\"doi\":\"10.46940/snnsj.02.1002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Piracetam (2-oxo-1-pyrrolidine acetamide) is a cyclical derivative of GABA (gamma-aminobutyric acid). It was first synthesized during the 1950s by Corneliu E. Giurgea. There are reports of its use for epilepsy in the 1950s. Piracetam can beneficially influence impaired brain function by improving neuronal and cognitive functions without acting as a sedative or stimulant, increasing blood flow and oxygen consumption in the brain and improving the function of the neurotransmitters and brain neurotransmission.\",\"PeriodicalId\":280856,\"journal\":{\"name\":\"SunKrist Neurology, Neurosurgery and Stroke Journal\",\"volume\":\"49 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SunKrist Neurology, Neurosurgery and Stroke Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46940/snnsj.02.1002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SunKrist Neurology, Neurosurgery and Stroke Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46940/snnsj.02.1002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
吡拉西坦(2-氧-1-吡咯烷乙酰胺)是GABA (γ -氨基丁酸)的周期性衍生物。它是在20世纪50年代由Corneliu E. Giurgea首次合成的。在20世纪50年代，有报道称其用于治疗癫痫。吡拉西坦可以改善神经和认知功能，而不作为镇静剂或兴奋剂，增加脑血流量和耗氧量，改善神经递质和脑神经传递的功能，从而有益地影响受损的脑功能。
Abstract Piracetam (2-oxo-1-pyrrolidine acetamide) is a cyclical derivative of GABA (gamma-aminobutyric acid). It was first synthesized during the 1950s by Corneliu E. Giurgea. There are reports of its use for epilepsy in the 1950s. Piracetam can beneficially influence impaired brain function by improving neuronal and cognitive functions without acting as a sedative or stimulant, increasing blood flow and oxygen consumption in the brain and improving the function of the neurotransmitters and brain neurotransmission.
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