复方多糖抗肿瘤活性及其作用机制研究

Man Li
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引用次数: 0

摘要

近年来,恶性肿瘤已成为严重危害健康和致死的头号重大疾病。恶性肿瘤的治疗方法主要有手术、放疗和化疗。然而,放射治疗和化疗具有特异性差和损害机体免疫功能的缺点。因此,制备低毒、疗效好的抗癌活性成分,可以保护和提高肿瘤患者的免疫功能。特别是提高患者的细胞免疫功能,减少放化疗的毒副作用,对预防肿瘤的发生,提高肿瘤的治疗效果具有重要意义。大量研究表明,多糖具有增强免疫功能和抗肿瘤作用。不同来源的植物多糖具有不同的作用机制。不同的多糖按一定的比例配制成混合制剂。进入体内后,通过不同途径提高机体的抗肿瘤、抗辐射作用,并探索其作用机制,为肿瘤患者的临床治疗提供重要的实验依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study on Antitumor Activity and Mechanism of Compound Polysaccharide
In recent years, malignant tumors have become the number one major disease that seriously endangers health and causes death. The main methods for the treatment of malignant tumors are surgery, radiotherapy and chemotherapy. However, radiation therapy and chemotherapy have the disadvantages of poor specificity and damage to the immune function of the body. Therefore, the preparation of anti-cancer active ingredients with low toxicity and good efficacy can protect and improve the immune function of tumor patients. In particular, it is of great significance to improve the cellular immune function of patients and to reduce the toxic and side effects of radiotherapy and chemotherapy for preventing the occurrence of tumors and improving the therapeutic effect of tumors. A large number of studies have shown that polysaccharides can enhance immune function and anti-tumor effects. Plant polysaccharides from different sources have different mechanisms. Different polysaccharides are formulated into a mixed preparation according to a certain ratio. After entering the body, the anti-tumor and anti-radiation effects of the body will be improved through different approaches, and the mechanism of action will be explored, which will provide important experimental basis for clinical treatment of tumor patients.
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