小儿淋巴畸形的治疗体会

J. H. Park, S. Nam
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引用次数: 1

摘要

目的:小儿淋巴畸形(LM)的治疗具有挑战性。在某些情况下,完全切除LM是困难的。我们回顾了如何管理LM的经验。方法:回顾性分析2010年至2017年期间接受LM治疗的患者。回顾患者的诊断年龄、治疗年龄、性别、症状、肿瘤部位、治疗方式、疗效及并发症。结果:共纳入63例患者,其中男39例,女24例。诊断时平均年龄14.5±28.0个月(范围:新生儿-10岁)。累及病灶为头颈部27例(42.9%)、腹腔7例(11.1%)、胸壁和腹壁11例(17.5%)、臀部7例(11.1%)、四肢11例(17.5%)。治疗方案包括手术切除32例,硬化剂治疗7例,手术切除联合硬化剂治疗19例,密切观察5例。我们在39例患者中实现了完全缓解。14例部分缓解,6例复发。结论:尽管手术困难,但精细切除配合支持治疗和辅助硬化治疗可获得良好的预后,无致命并发症。决定应基于外科医生的经验,LM的位置,相关症状,并咨询患者的父母。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Treatment Experience of Lymphatic Malformations in Pediatric Patients
Purpose: The management of lymphatic malformation (LM) in pediatric patients is challenging. Complete excision of LM is difficult to achieve in some cases. We reviewed our experience how to manage LM. Methods: We retrospectively reviewed the patients who were treated for LM between 2010 and 2017. Medical records were reviewed about age of diagnosis, age of treatment age, gender, symptom, location of tumor, treatment modality, response and complication. Results: Sixty-three patients (39 boys and 24 girls) were included. Mean age at diagnosis was 14.5±28.0 months (range, neonate-10 years). The involved lesion were head and neck in 27 patients (42.9%), abdominal cavity in 7 patients (11.1%), chest wall and abdominal wall in 11 patients (17.5%), buttock in 7 patients (11.1%), and extremities in 11 patients (17.5%). The treatment options were including surgical resection in 32 patients, sclerotherapy in 7 patients, surgical resection combined sclerotherapy in 19 patients, and close observation in 5 patients. We achieved complete remission in 39 patients. Fourteen patients showed partial remission and 6 showed recurrences. Conclusion: Despite surgical difficulty, meticulous excision with supportive treatment, and adjuvant sclerotherapy could get a favorable outcome without fatal complication. Decision should be based on surgeon’s experience, location of LM, related symptoms, and consultation with patient’s parents.
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