Long range predictive control of arterial blood pressure

A multistep adaptive predictive controller has been experimentally evaluated for control of blood pressure. The purpose of this controller is to control the mean arterial pressure under hypertensive conditions, using sodium nitroprusside to maintain the pressure at a desired lower level. The development of the controller makes use of a real-time multitasking software environment which allows operators to make changes on-line. Experiment results show that the controller is efficient in both set point tracking and regulatory control. Its long-range predictive nature also makes the system more robust in dealing with unknown and varying time delay as well as nonminimum phase processes.<>