{"title":"合成的s -三嗪衍生物抑菌活性优化","authors":"G. Swami, K. Bothara","doi":"10.33289/ijrpc.9.4.2019.981","DOIUrl":null,"url":null,"abstract":"The emergence of new infectious diseases, the resurgence of several infections that appeared to have been controlled and the increase in bacterial resistance have created the necessity for studies directed towards the development of new potential antimicrobials. A series of novel sTriazine has been synthesized and screened for antimicrobial activities. The compound R3 and R10 obtained optimum antibacterial activity against S. aureus; compound R5 obtained optimum antibacterial activity against Pseudomonas aeruginosa and compound R6 obtained optimum antibacterial activity against Bacillus substilis, S. aureus and moderate activity against E. coli and P. aeruginosa at 25ug/ml concentration","PeriodicalId":137879,"journal":{"name":"International Journal of Research in Pharmacy and Chemistry","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"OPTIMIZATION OF ANTIMICROBIAL ACTIVITY OF SYNTHESIZED S-TRIAZINE DERIVATIVES\",\"authors\":\"G. Swami, K. Bothara\",\"doi\":\"10.33289/ijrpc.9.4.2019.981\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The emergence of new infectious diseases, the resurgence of several infections that appeared to have been controlled and the increase in bacterial resistance have created the necessity for studies directed towards the development of new potential antimicrobials. A series of novel sTriazine has been synthesized and screened for antimicrobial activities. The compound R3 and R10 obtained optimum antibacterial activity against S. aureus; compound R5 obtained optimum antibacterial activity against Pseudomonas aeruginosa and compound R6 obtained optimum antibacterial activity against Bacillus substilis, S. aureus and moderate activity against E. coli and P. aeruginosa at 25ug/ml concentration\",\"PeriodicalId\":137879,\"journal\":{\"name\":\"International Journal of Research in Pharmacy and Chemistry\",\"volume\":\"21 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-10-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Research in Pharmacy and Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33289/ijrpc.9.4.2019.981\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Research in Pharmacy and Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33289/ijrpc.9.4.2019.981","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
OPTIMIZATION OF ANTIMICROBIAL ACTIVITY OF SYNTHESIZED S-TRIAZINE DERIVATIVES
The emergence of new infectious diseases, the resurgence of several infections that appeared to have been controlled and the increase in bacterial resistance have created the necessity for studies directed towards the development of new potential antimicrobials. A series of novel sTriazine has been synthesized and screened for antimicrobial activities. The compound R3 and R10 obtained optimum antibacterial activity against S. aureus; compound R5 obtained optimum antibacterial activity against Pseudomonas aeruginosa and compound R6 obtained optimum antibacterial activity against Bacillus substilis, S. aureus and moderate activity against E. coli and P. aeruginosa at 25ug/ml concentration
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