偏头痛患者的听觉脑干诱发反应

D. Kaushaln, S. Munjal, M. Modi, N. Panda
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引用次数: 5

摘要

偏头痛是一种痛苦的神经系统疾病,偏头痛的发病机制尚不完全清楚。一些研究人员认为大脑皮层可能参与其中,而另一些人则认为是脑干的责任。目的:本研究的目的是评估偏头痛患者脑干听觉诱发电位。方法:选取25例年龄在10-45岁之间,诊断为偏头痛(有或无先兆)的患者作为研究组。在这25名受试者中,6名(4名男性,2名女性)受试者在测试期间报告头痛。对照组由25名健康受试者组成,年龄在10至45岁之间,无偏头痛主诉。用插入式耳塞记录脑干听觉诱发电位。结果:研究组与对照组的绝对潜伏期差异有统计学意义。同样,在对照组和研究组之间的峰间潜伏期也得到了显著的结果。在ABR测试中发现急性偏头痛发作的受试者峰间潜伏期延长。结论:偏头痛发作时脑干结构受累,ABER波的峰间潜伏期延长支持了这一结论。因此,听觉脑干诱发反应可作为对听觉通路进行神经生理评价的有效工具,在解释偏头痛的病理生理中发挥重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Auditory Brainstem Evoked Responses In Migraine Patients
INTRODUCTION:Migraine is a painful neurological condition and the pathogenesis of migraine is not completely understood. Some researchers are of opinion that cortex may be involved whereas others hold the brainstem responsible.AIM:The aim of the present study was to evaluate the brainstem auditory evoked potentials in patients with migraine.METHODOLOGY:25 patients in the age range of 10-45 years, diagnosed as having migraine (with or without aura) were taken as the study group. Out of these 25 subjects, 6 (4 males, 2 females) subjects reported headache during the testing period. Control group consisted of 25 healthy subjects in the age range of 10 to 45 years with no complaint of migraine. Brainstem auditory evoked potentials were recorded using insert ear phones.RESULTS:There was a significant difference between absolute latencies of study group and control group. Similarly, significant results were obtained for interpeak latencies between control and study group. It was observed that prolongation in interpeak latency was reported in those subjects who had an acute attack of migraine during ABR testing.CONCLUSION :It is concluded that there is an involvement of brainstem structures during migraine attack and this is supported by the prolongation of interpeak latencies of waves in ABER. Therefore, Auditory brainstem evoked responses can be used as an effective tool in making the neurophysiological evaluation of the auditory pathway which further plays an important role in the explanation of pathophysiology of migraine.
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