Heterotopic ossification may occur due to forcible physical therapy

Heterotopic ossification (HO) is a condition in which bones form in the muscle and soft tissues where normally bones should not exist. The etiology of this disease, which was described about 100 years ago, has not been fully revealed despite the time elapsed.[1,2] Heterotopic ossification is generally studied in three groups: neurogenic HO, traumatic HO, and myositis ossificans progressiva.[1] Neurogenic HO mostly accompanies head and spine injuries and some neurological diseases. Traumatic HO occurs after surgical interventions and trauma. Myositis ossificans progressiva is a disease with an autosomal dominant inheritance that involves muscles, ligaments, and tendons, and it can be mortal.[2]