应激性心肌病:由多种诱因引起的相同病理。

A. Ullah, N. Malik, D. Fraser, A. Raza, F. Ordoubadi, M. Omar
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引用次数: 0

摘要

应激性心肌病(SCM),也被称为Takatsubo心肌病或心碎综合征,自其第一次被描述以来,文献中已经有了很好的记录。随着对该病认识的提高和证据基础的增加,近年来报道的SCM发病率稳步上升,目前估计为急性冠脉综合征患者的1- 2%。有不同的标准提出诊断应激性心肌病和这解决或多或少相同的临床问题,而诊断这并不罕见的条件。尽管进行了广泛的研究,但对SCM的确切机制和致病因素仍缺乏了解。我们报告的各种情况下,一个不同的触发似乎已经负责SCM的因果关系。似乎不管最初的诱因是什么,最终的临床表现和过程都是一样的。这些进一步加强了这种情况是由易感个体的共同神经心血管途径介导的观点。进一步探索这些机制对于改善我们的策略,试图预防和有效地管理这种潜在的致残状况至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stress cardiomyopathy: Same pathology caused by variety of triggers.
Stress cardiomyopathy (SCM), also known as Takatsubo cardiomyopathy or broken heart syndrome has been well documented in literature since its first description. With more awareness of the condition and increasing evidence base, the reported incidence of SCM has steadily increased over years and currently estimated at 1-2 % of the patients presenting with acute coronary syndrome. There are different criteria proposed for diagnosis of stress cardiomyopathy and this address more or less the same clinical questions while diagnosing this not so uncommon condition. Despite extensive research , there has been a lack of understanding on the exact mechanism and causative factors leading to SCM. We report a variety of cases where  a different trigger appears to have been responsible for causation of SCM. It would seem that irrespective of the original trigger, the final clinical picture and course remains identical. These further strengths the idea that the condition is mediated by a common neurocardiovacular pathway in susceptible individuals. Further exploration of these mechanisms would be crucial to improve our strategies to try to prevent and effectively manage this potentially disabling condition.
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