肥厚性心肌病异常Q波发生的心肌各向异性:模拟研究

Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269) Pub Date : 1998-02-15 DOI:10.1109/ICBEM.1998.666456

D. Wei, N. Miyamoto, S. Mashima

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引用次数: 1

摘要

采用全心模型进行计算机模拟，研究肥厚性心肌病(HCM)异常Q波的发生机制。根据临床超声心动图对HCM的解剖特征进行建模。根据病理结果模拟了肥厚组织各向异性和其他电生理特性的可能变化。通过假设肥厚组织中的纤维取向各向同性，并通过改变正常值的其他特性，可以获得显示HCM主要特征的模拟心电图。本研究提出了一种解释HCM异常Q波的可能机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Myocardial anisotropy in genesis of abnormal Q waves in hypertrophic cardiomyopathy: a simulation study

Computer simulation with a whole-heart model was conducted to study genesis of abnormal Q waves in hypertrophic cardiomyopathy (HCM). The anatomic feature of HCM was modeled based on clinical echocardiogram images. Possible changes in anisotropy as well as in other electrophysiologic properties in hypertrophic tissue were simulated based on pathologic findings. Simulated ECGs showing the main features of HCM were obtained by assuming isotropic fiber orientation in hypertrophic tissue and by changing other properties from normal values. This study suggests a possible mechanism to account for abnormal Q waves in HCM.

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Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)

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