【寻常型银屑病中肩环角化细胞未见异常分化】。

Dermatologische Monatschrift Pub Date : 1990-01-01
U Wollina, H Schaarschmidt, B Knopf, C Hipler
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引用次数: 0

摘要

组织化学研究在正常和银屑病表皮中进行,以评估顶针反应性的可能差异。细胞内(富含糖缀合物,免疫反应性)和外(几乎无反应性)上皮细胞可以区分。银屑病不影响染色模式。研究结果反驳了顶针角化细胞在银屑病表皮细胞异常分化途径中的主要参与。此外,它们还强调了顶毛相对于毛囊间表皮的独立性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Acrosyringial keratinocytes--no abnormal differentiation in psoriasis vulgaris].

Histochemical investigations were performed in normal and psoriatic epidermis to evaluate possible differences in the acrosyringial reactivity. Luminal (abundant in glycoconjugates, immunoreactive) and outer (almost nonreactive) epithelial cells could be distinguished. Psoriasis did not affect the staining pattern. The findings argue against a primary involvement of acrosyringial keratinocytes in the abnormal differentiation pathway of psoriatic epidermal cells. Moreover, they underline the relative independence of the acrosyringium from interfollicular epidermis.

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