免疫疗法治疗癌症,一个有希望的治愈方法?

Xinlan Yang
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引用次数: 0

摘要

癌症是世界上常见的死亡原因。迄今为止,手术仍然是大多数癌症的唯一治疗选择。此外,大多数癌症对我们长期使用的传统疗法,包括化疗和放疗,都有明显的耐药性。近年来,不同类型的免疫细胞已被认为是治疗的关键组成部分。特别是癌症免疫治疗已成为人们关注的焦点。在许多临床试验中,它已经显示出解决过渡疗法缺陷的能力,实现肿瘤的完全根除,并建立持久的免疫力来防止复发。目前,在方法和途径方面取得了显著进展和创新。在本文中,我们首先讨论了参与抗肿瘤/癌症活动的主要免疫细胞类型,免疫治疗及其在多个领域的应用。接下来,我们总结了免疫系统与癌症之间的联系,以及目前针对癌症的免疫疗法,包括具体的例子或实验试验,以及每种疗法的优缺点。尽管免疫治疗有许多未解决的问题,如财政问题,但本文总体上表明,免疫治疗的发展是一种新兴的、潜在的影响癌症生存率和预后的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunotherapies For Cancer, a Promising Cure?
Cancer is a common cause of death around the world. To date, surgery is still the only curative option for most types of cancer. Moreover, the majority of cancer is a prominent resistance to traditional therapies that we have long been using, including chemotherapy and radiotherapy. In recent years, different types of immune cells have been recognized as a critical component in therapies. Especially, the cancer-immunotherapy has come into the spotlight. In a number of clinical trials, it has shown capabilities of addressing the defects of transitional therapies, achieving complete eradication of neoplasms and constructing a long-lasting immunity to prevent recurrence. Currently, remarkable progress and innovations in methods and approaches are made. In this article, we first discuss the main types of immune cells participated in anti-tumor/cancer activities, immunotherapy and its applications in multiple fields. Next, we summarize the associations between the immune system and cancer, and current immunotherapies for cancer, including specific examples or experimental trials, with the advantages and disadvantages of each. Despite many unsolved questions regarding immunotherapy such as financial concerns, the current paper overall demonstrates that the development of immunotherapy is an emerging and potentially influential therapy for improving the survival rate and prognosis of cancer.
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