Yen Sun, Sung-Jan Lin, Chih-Yuan Hsiao, Wen Lo, S. Jee, C. Dong
{"title":"二次谐波生成显微镜对热诱导胶原结构转变的研究","authors":"Yen Sun, Sung-Jan Lin, Chih-Yuan Hsiao, Wen Lo, S. Jee, C. Dong","doi":"10.1109/APBP.2004.1412339","DOIUrl":null,"url":null,"abstract":"In this work, the thermal disruption of type I collagen is investigated using second harmonic generation (SHG) microscopy. We investigated the effects of second harmonic generation images and intensity of rat tail tendon in the temperature range from 25 to 60/spl deg/C. We found a structural transition at 57/spl deg/C where a drop in second harmonic intensity is correlated to a disorganization of the collagen fibers. Our results suggest that SHG microscopy is an effective technique to monitor thermally induced collagen structural changes for biomedical applications.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"187 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An investigation of thermally induced collagen structural transitions by second harmonic generation microscopy\",\"authors\":\"Yen Sun, Sung-Jan Lin, Chih-Yuan Hsiao, Wen Lo, S. Jee, C. Dong\",\"doi\":\"10.1109/APBP.2004.1412339\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this work, the thermal disruption of type I collagen is investigated using second harmonic generation (SHG) microscopy. We investigated the effects of second harmonic generation images and intensity of rat tail tendon in the temperature range from 25 to 60/spl deg/C. We found a structural transition at 57/spl deg/C where a drop in second harmonic intensity is correlated to a disorganization of the collagen fibers. Our results suggest that SHG microscopy is an effective technique to monitor thermally induced collagen structural changes for biomedical applications.\",\"PeriodicalId\":346624,\"journal\":{\"name\":\"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.\",\"volume\":\"187 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/APBP.2004.1412339\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/APBP.2004.1412339","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
An investigation of thermally induced collagen structural transitions by second harmonic generation microscopy
In this work, the thermal disruption of type I collagen is investigated using second harmonic generation (SHG) microscopy. We investigated the effects of second harmonic generation images and intensity of rat tail tendon in the temperature range from 25 to 60/spl deg/C. We found a structural transition at 57/spl deg/C where a drop in second harmonic intensity is correlated to a disorganization of the collagen fibers. Our results suggest that SHG microscopy is an effective technique to monitor thermally induced collagen structural changes for biomedical applications.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
