早期诊断过程中患者降钙素原测量的特点

Małgorzata Timler, Katarzyna Szwabe, Wojciech Timler, D. Timler
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引用次数: 0

摘要

目的:介绍在急诊就诊的患者中,其主治医生决定评估PCT水平的人群。材料和方法:所有数据收集于2022年4月1日至2022年4月30日。纳入标准在入急诊科时进行PCT测量。记录以下数据:年龄、性别、体温、血压、心率、SpO2、呼吸频率、格拉斯哥昏迷量表,诊断:肺炎、尿路感染、糖尿病、SARS-Cov-2感染、PCT水平、c反应蛋白水平、白细胞水平、肾小球滤过率。PCT正常上限为0.05 μg/L, C-反应蛋白正常上限为5 mg/dL,白蛋白正常上限为4 ~ 10 G/dL。结果:研究组PCT水平升高68例(83%)。PCT水平升高的患者年龄较大,血压较低,c反应蛋白浓度升高较多。这些病人往往有更高的住院死亡率。结论:经急诊医师评估后,大多数患者的PCT水平升高。白细胞数量异常和体温高于37℃对PCT升高无预测价值,PCT升高可能提示院内死亡风险增加。需要制定PCT使用的简单指南,并在日常临床实践中加以实施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CHARACTERISTICS OF PATIENTS WITH PROCALCITONIN MEASUREMENTS DURING EARLY DIAGNOSIS PROCESS
Aim: To present the population of patients admitted to the Emergency Department in whom their attending physician decided to assess PCT level. Material and methods: All data were collected between 01/04/2022 and 30/04/2022. The inclusion criterion was performed PCT measurement at admission to the Emergency Department. The following data were noted: age, gender, temperature, blood pressure, heart rate, SpO2, respiratory rate, Glasgow Coma Scale, the diagnosis: pneumonia, infection tractus urinary, diabetes, SARS-Cov-2 infection, PCT level, C-reactive protein level, leucocyte level, glomerular filtration rate. PCT upper normal limit was 0.05 μg/L, C- reactive protein upper limit was 5 mg/dL and leucite number was between 4 and 10 G/dL. Results: PCT level was increased in 68 (83%) of the studied group. The patients with increased PCT level are older, have lower blood pressure and more often increased C-reactive protein concentration. These patients tended to have increased in-hospital mortality. Conclusions: PCT level was increased in the majority of patients in whom this parameter was assessed by emergency physicians. Abnormal leucocyte number and the presence of temperature above 37 Celsius degree had no prediction value of presence of increased PCT. Increased PCT level may indicate the increased risk of the in hospital death. Simple guidelines for PCT usage need to be created and implemented in everyday clinical practice.
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