Medhavi Honhar, J. Herring, Amna Qasim, V. Modi, María E. Franco-Fuenmayor, Sunil K. Jain
{"title":"肠内喂养是早产儿内源性一氧化氮产生的一个不良底物来源-一项试点研究","authors":"Medhavi Honhar, J. Herring, Amna Qasim, V. Modi, María E. Franco-Fuenmayor, Sunil K. Jain","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.699","DOIUrl":null,"url":null,"abstract":"Background: Bronchopulmonary dysplasia (BPD) prevalence has increased with an increase in the survival of premature infants (PI). BPD associated PH (BP-PH) occurs in 1/4th of the infants with BPD due to high pulmonary vascular resistance (PVR). The endogenous NO production helps with decreasing the PVR. L-arginine (Arg) and L-citrulline (Cit) helps with the production of endogenous nitric oxide (NO). We speculate PI with BPD needs more NO to reduce PVR compared to infants without BPD which makes Arg/Cit as a semi-essential amino acid in infants with BPD-PH. TPN contains …","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"28 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enteral Feed Is A Poor Source of Substrates For Endogenous Nitric Oxide Production In Preterm Infants – A Pilot Study\",\"authors\":\"Medhavi Honhar, J. Herring, Amna Qasim, V. Modi, María E. Franco-Fuenmayor, Sunil K. Jain\",\"doi\":\"10.1542/PEDS.147.3_MEETINGABSTRACT.699\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Bronchopulmonary dysplasia (BPD) prevalence has increased with an increase in the survival of premature infants (PI). BPD associated PH (BP-PH) occurs in 1/4th of the infants with BPD due to high pulmonary vascular resistance (PVR). The endogenous NO production helps with decreasing the PVR. L-arginine (Arg) and L-citrulline (Cit) helps with the production of endogenous nitric oxide (NO). We speculate PI with BPD needs more NO to reduce PVR compared to infants without BPD which makes Arg/Cit as a semi-essential amino acid in infants with BPD-PH. TPN contains …\",\"PeriodicalId\":275302,\"journal\":{\"name\":\"Section on Neonatal-Perinatal Medicine Program\",\"volume\":\"28 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Section on Neonatal-Perinatal Medicine Program\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.699\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Section on Neonatal-Perinatal Medicine Program","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.699","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Enteral Feed Is A Poor Source of Substrates For Endogenous Nitric Oxide Production In Preterm Infants – A Pilot Study
Background: Bronchopulmonary dysplasia (BPD) prevalence has increased with an increase in the survival of premature infants (PI). BPD associated PH (BP-PH) occurs in 1/4th of the infants with BPD due to high pulmonary vascular resistance (PVR). The endogenous NO production helps with decreasing the PVR. L-arginine (Arg) and L-citrulline (Cit) helps with the production of endogenous nitric oxide (NO). We speculate PI with BPD needs more NO to reduce PVR compared to infants without BPD which makes Arg/Cit as a semi-essential amino acid in infants with BPD-PH. TPN contains …
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
