生物技术实验室完整样本管理的自动化

Martin Wojtczyk, Michael Marszalek, A. Knoll, R. Heidemann, K. Joeris, Chun Zhang, M. Burnett, T. Monica
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引用次数: 4

摘要

机器人和个人电脑都在大约30年前建立了新的市场,并成为自动化和信息技术的推动因素。然而,虽然你现在几乎可以在每个家庭看到个人电脑,但机器人的领域总体上仍然主要局限于工业自动化。由于机器人的物理影响,安全的设计是必不可少的,这是大多数机器人仍然缺乏的,因此阻碍了它们的个人使用,尽管可以通过引入用于特定任务的专用机器人来注意到缓慢的变化,这可以归类为服务机器人。我们的服务机器人的方法是由支持生物技术实验室的实验室人员的想法驱动的。这导致了机械手与移动平台的结合,扩展了必要的传感器,以在哺乳动物细胞培养工厂中执行完整的样品管理过程。在德国进行初步开发后,移动机械手被运往位于美国加州伯克利的拜耳医疗保健公司,拜耳医疗保健公司是生物制药产品领域的全球参与者,位于旧金山湾区。该平台已安装到位,并在一家中试工厂成功进行了测试。这个项目展示了信息技术和机器人这两项关键技术的成功结合,以及它在生命科学试点工厂的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Automation of the Complete Sample Management in a Biotech Laboratory
Both Robots and Personal Computers established new markets about 30 years ago and were enabling factors in Automation and Information Technology. However, while you can see Personal Computers in almost every home nowadays, the domain of Robots in general still is mostly restricted to industrial automation. Due to the physical impact of robots, a safe design is essential, which most robots still lack of and therefore prevent their application for personal use, although a slow change can be noticed by the introduction of dedicated robots for specific tasks, which can be classified as service robots. Our approach to service robots was driven by the idea for supporting lab personnel in a biotechnology laboratory. That resulted in the combination of a manipulator with a mobile platform, extended with the necessary sensors to carry out a complete sample management process in a mammalian cell culture plant. After the initial development in Germany, the mobile manipulator was shipped to Bayer HealthCare in Berkeley, CA, USA, a global player in the sector of biopharmaceutical products, located in the San Francisco bay area. The platform was installed and successfully tested there in a pilot plant. This project demonstrates the successful combination of both key technologies: Information Technology and Robotics - and its application in a Life Science pilot plant.
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