子宫内膜癌中选定脂肪因子基因表达模式的改变

Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed. Pub Date : 2021-11-19 DOI:10.3390/mol2net-07-11834

Robert Kiełbasiński, B. Grabarek, Krzysztof Balawender, D. Boroń

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摘要

摘要Leptin (LEP)主要由分化的脂肪细胞分泌，通过激活JAK/STAT通路影响肿瘤血管生成，导致血管内皮细胞增殖增加，血管内皮生长因子(VEGF)表达增加。

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Changes in the expression pattern of genes encoding selected adipokines in endometrial cancer

Abstract. Leptin (LEP) is primarily secreted by differentiated adipocytes, influencing neoplastic angiogenesis through the activation of the JAK/STAT pathway, which results in the increased proliferation of vascular endothelial cells as well as an increased expression of the vascular endothelial growth factor (VEGF),

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Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.

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