Effects of Targeted Temperature Management on Drugs

Hypothermia therapy, better known as targeted temperature management (TTM), has increased in popularity in the past several years and has only proven benefits in the setting of cardiac arrest. It has been unsuccessful or not sufficiently proven in traumatic brain injury,bacterial meningitis, cerebral hemorrhage and ischemic stroke. TTM has been shown to decrease intracranial pressure and is used in the management of refractory intracranial pressure despite recent evidence suggesting harm.