Motif搜索MapReduce和MPI程序的开发

Mejdl S. Safran, Saad Al-qahtani, Michelle Zhu, D. Che
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摘要

作为分子生物学中的重要问题之一,基序搜索的计算成本非常高,特别是当DNA序列的大小很大时。本文从并行和分布式计算(PDC)的研究生课程项目扩展,研究了两种不同的编程框架,即MapReduce和MPI在motif查找方面的应用。我们实现了一个串行算法、一个基于MapReduce的算法和一个MPI程序来计算给定DNA序列中的最佳基序。实验结果表明,我们的MPI程序比基于mapreduce的算法和串行程序都具有更高的效率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development of MapReduce and MPI Programs for Motif Search
As one of the important problems in molecular biology, motif search is computationally expensive, especially when the size of DNA sequences is large. Extended from a graduate course project in parallel and distributed computing (PDC), this paper investigates two different programming frameworks, namely MapReduce and MPI on motif finding. We implemented a serial algorithm, a MapReduce based algorithm, and a MPI program to calculate the best motif in given DNA sequences. The experimental results demonstrate that our MPI program outperformed both the MapReduce-based algorithm and the serial program with superior efficiency.
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