胸部计算机断层扫描对一家Covid-19参考医院的影响-第一波-联邦-巴西

Gleim Dias de Souza, Luciana Rodrigues Queiroz De Souza, Gabriela Gomes De Souza, Thales Queiroz Souza, Ulysses Rodrigues Castro, Adriano Guimaraes Ibiapina, Paulo Henrique Ramos Feitosa, S. Ajzen
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引用次数: 0

摘要

目的评价胸部CT与临床表现及与PCR-RT相关的诊断COVID-19的准确性。评估敏感性、特异性、阳性预测值和阴性预测值、性别、年龄组和肺部受累程度。方法对1545例胸部CT患者进行评估,确定年龄范围和肺部受累程度,并对306例胸部CT和PCR-RT进行评估。结果在1545例检查中,53%为男性,47%为女性,其中50-59岁年龄组参与较多。在肺部研究中,55.05%为COVID-19。轻度占37.70%,中度占35.76%,重度占26.54%。在年龄分布中,50-59岁的患者受累较多,其中中度(27.6%)和重度(28.0%)占56%。ct与PCR-RT的敏感性68.8%,特异性59.5%,准确性91.3%,患病率31.9%,阳性预测值44.3%,阴性预测值80.3%,女性敏感性55.3%,阳性预测值37.1%,阴性预测值75.3%,男性敏感性81.6%,阳性预测值50,6,阴性预测值86.6%。性别间敏感性差异较大,p值为0.005,特异度为0.938,受年龄影响,45岁时敏感性和特异度p值为0.057,80岁时敏感性和特异度p值降至0.006。结论与PCR-RT相比,CT扫描的敏感性和准确性均有显著提高。敏感性随着患病率的增加而增加,在老年群体和男性中也是如此。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of Chest Computed Tomography in A Covid-19 Reference Hospital - First Wave - Distrito Federal - Brazil
Objectives To evaluate the diagnostic accuracy of chest CT for the diagnosis of COVID-19 associated with the clinical presentation and in relation to the PCR-RT. Sensitivity, specificity, positive predictive value and negative predictive value, gender, age group and degree of lung involvement will be evaluated. Methods We evaluated 1545 patients with chest CT, delineating the age range and degree of lung involvement, and 306 patients with chest CT and PCR-RT. Results Of the 1545 examinations, 53% were men and 47% were women, there was greater involvement in the 50-59 age group. In the pulmonary study, 55.05% were COVID-19. In the degree of lung involvement 37.70% were mild, 35.76% were moderate, and 26.54% were severe. In the distribution by age, there was a greater involvement between 50-59 years with 56% between moderate (27.6%) and severe (28.0%). Between tomography and PCR-RT, the sensitivity was 68.8%, specificity 59.5%, accuracy 91.3%, with prevalence 31.9%, positive predictive value 44.3% and negative predictive value 80.3%, in females, sensitivity 55.3%, positive predictive value 37.1%, negative predictive value 75.3%, in males, sensitivity 81.6%, positive predictive value 50, 6 and negative predictive value 86.6%.The sensitivities are different between the genders with p of 0.005 and specificity of 0.938, with age effect, starting at 45 years we have a p of 0.057 that decreases to 0.006 at 80 years for sensitivity and specificity. Conclusions The sensitivity and accuracy of CT scan in relation to PCR-RT was significant. Sensitivity increases with prevalence and in the older age group and in men.
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