Dental pulp revascularization of an open-apex maxillary central incisor in a patient in the fifth decade

This report presents a case of revascularization of an open-apex maxillary central incisor in a 46-year-old patient using concentrated growth factor (CGF). After disinfection protocol, the apical foramen was mechanically enlarged, and autologous CGF gel was prepared and placed into the root canal to a level close to the cementoenamel junction. The follow-up evaluation confirmed the clinical success of the treatment with the restoration of tooth sensation within 6 months. The previous flat-shaped apex morphology of the tooth changed into a more rounded shape but with no real change in the length of the root or the size of the canal. This case report shows the potential of using the root canal revascularization technique to treat nonvital teeth in elder patients with the advantage of restoration of tooth sensation. The promising role of the CGF in sdental pulp regeneration is also highlighted.