根治性前列腺切除术和术后疼痛后硅胶膀胱导管与聚氯乙烯膀胱导管:一项随机比较研究

Marilena Mouriki, A. Papatsoris, Andreas Karagiannis, Aristeidis Karagiannis, P. Kamperi, C. Deliveliotis
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摘要

简介:前列腺癌是男性最常见的恶性肿瘤。在局限性前列腺癌的情况下,治疗的选择是根治性前列腺切除术。根治性前列腺切除术产生术后疼痛,其特征是由手术野引起的急性伤害性疼痛和由留置导尿管引起的导管相关性膀胱不适(CRBD)。本研究的目的是比较两种不同类型的留置膀胱导尿管对根治性耻骨后前列腺切除术后疼痛的影响。材料与方法:本研究纳入120例行根治性耻骨后前列腺切除术的局限性前列腺癌患者,随机分为两组,每组60例。第一组采用聚氯乙烯库维尔尿管(库维尔尿管组),第二组采用硅胶尿管(硅胶尿管组)。导尿采用20Fr导尿管,球囊充20ml。所有患者均给予吗啡、扑热息痛、罗哌卡因和氯诺昔康伤口浸润治疗术后疼痛。采用临床疼痛测量数值评定量表评估患者术后疼痛程度,并于术后1、2、6、24小时、3、5天将导管相关膀胱不适分为零、轻度、中度、重度。结果:硅胶组术后第6、24小时及第3、5天因组织损伤引起的疼痛明显低于courvelaire组。(P < 0.05)。硅胶组与导管相关的膀胱不适明显低于couvelaire组(P<0.001)。结论:与使用聚氯乙烯制成的couvelaire导尿管相比,使用纯硅胶导尿管可减轻根治性耻骨后前列腺切除术患者的术后疼痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Silicone versus polyvinylchloride bladder catheter following radical prostatectomy and postoperative pain: a randomized comparative study
Introduction: Prostate cancer is the most common malignancy in men. In the case of localized prostate cancer, the treatment of choice is radical prostatectomy. Radical prostatectomy creates post-operative pain which is characterized as acute nociceptive resulting from the surgical field and catheter-related bladder discomfort (CRBD) resulting from the indwelling urinary catheter. The purpose of the study was the comparison of the effect of two different types of indwelling bladder catheters on postoperative pain after radical retropubic prostatectomy. Materials and Methods: The study included 120 men with localized prostate cancer who underwent radical retropubic prostatectomy and were randomized into two groups of 60 each. In the first group patients were catheterized with a couvelaire urinary catheter made of polyvinylchloride (couvelaire group) and in the second group patients were catheterized with a silicone catheter (silicone group). Urinary catheterization was performed with a 20Fr catheter and the balloon was inflated with 20ml. All patients received morphine, paracetamol , wound infiltration with ropivacaine and lornoxicam for the treatment of postoperative pain. The grade of postoperative pain was assessed with the numeric rating scale for clinical pain measurement , and the catheter related bladder discomfort was assessed as null, mild, moderate and severe at the 1st, 2nd, 6th, 24th hour, 3rd and 5th day postoperatively. Results: The postoperative pain because of tissue damage was lower in the silicone group than that of the couvelaire group at 6th, 24th hour and 3rd, 5th day postoperatively. (P<0.05). The catheter related bladder discomfort was significantly lower in the silicone group than that of the couvelaire group (P<0.001). Conclusion: The use of urinary catheter made of pure silicone reduced postoperative pain in patients undergoing radical retropubic prostatectomy compared to the use of the couvelaire catheter made of polyvinylchloride.
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