Bahar Bassiri Gharb, A. Rampazzo, J. Kutz, B. Blair, R. Ouseph, M. Marvin, C. Kaufman
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Significance and Management of Low Grade Rejection in Hand Transplantation
Episodes of mild cellular rejection represent the majority of the acute rejection events in vascularized composite allotransplantation. Management of low grade rejection still represents a therapeutic challenge as an aggressive treatment can accelerate the occurrence of side effects of the systemic immunosuppressive therapy. In absence of clinical signs, the natural evolution of histologically diagnosed grade I rejection is not well understood.
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