血小板减少性紫癜和横纹肌溶解与甲状腺功能减退的急性肾功能衰竭有关

Jeonghun Lee, K. Lee, Sung Min Yun, Hyunchoon Shin, S. Nam, N. Cho
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引用次数: 2

摘要

甲状腺功能减退引起的肌病可以在早期发现,但由于症状轻微,并发症如横纹肌溶解是罕见的。甲状腺功能减退引起的血栓性血小板减少性紫癜尚未明确定义,有罕见病例报道。本文报告一例血栓性血小板减少性紫癜和横纹肌溶解合并急性肾功能衰竭甲状腺功能减退症。一名70岁男性因全身无力和肌肉疼痛入院。后来,根据实验室检查结果,他被诊断为横纹肌溶解合并急性肾功能衰竭和血栓性血小板减少性紫癜合并甲状腺功能减退。最初,由于横纹肌溶解合并急性肾功能衰竭,他接受了液体复苏治疗,但最终,左旋甲状腺素补充降低了促甲状腺激素水平。结果,患者在没有接受血浆置换治疗的情况下从横纹肌溶解和血栓性血小板减少性紫癜中康复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thrombotic Thrombocytopenic Purpura and Rhabdomyolysis Associated With Acute Renal Failure in Hypothyroidism
Myopathy due to hypothyroidism can be detected in its early stage, but as the symptom is mild, complications such as rhabdomyolysis are rare. Thrombotic thrombocytopenic purpura in hypothyroidism is not yet clearly defined, and rare cases of it are reported. Reported herein is a case of thrombotic thrombocytopenic purpura and rhabdomyolysis associated with acute renal failure in hypothyroidism. A 70-year-old male was admitted to the hospital due to general weakness and muscle pain. Later, based on the laboratory findings, he was diagnosed with rhabdomyolysis associated with acute renal failure and thrombotic thrombocytopenic purpura combined with hypothyroidism. Initially, he was treated with fluid resuscitation due to rhabdomyolysis combined with acute renal failure but eventually, the levothyroxine supplement lowered the thyrotropin-stimulating hormone level. As a result, the patient recovered from rhabdomyolysis and thrombotic thrombocytopenic purpura without receiving plasmapheresis treatment.
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