妊娠期寻常性天疱疮。一例罕见病例报告

Ioannis Kokolakis, Fanis Makrigiannakis, Sabine Kruger, K. Krasagakis, A. Makrigiannakis
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引用次数: 0

摘要

寻常型天疱疮(Pemphigus vulgaris, PV)是一种自身免疫性、大疱性、粘膜皮肤性和潜在威胁生命的疾病。妊娠期PV的发生极为罕见,由于母亲激素水平的不同以及治疗对母亲和胎儿的影响,其病情会变得更加复杂。PV可能与不良后果有关,如胎儿生长受限和早产。我们报告一例33岁的妇女谁是首次诊断为PV在怀孕期间。采用大剂量全身皮质类固醇治疗以控制疾病。她生下了一个健康的活早产儿,与胎龄相符,没有皮肤或粘膜病变或其他明显的并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pemphigusvulgaris in pregnancy. A rare case report
Pemphigus vulgaris (PV) is an autoimmune, bullous, mucocutaneous and potentially life-threatening disease. During pregnancy the occurrence of PV is exceedingly rare and its condition will become more complicated due to different mother’s hormone level and the effect of treatment on both mother and her fetus. PV may be associated with an adverse outcome, such as fetal growth restriction and preterm births. We report a case of a 33-year-old woman who was firstly diagnosed with PV during pregnancy. Treatment of highdoses systemic corticosteroids was instituted to control the disease. She delivered a healthy live preterm baby, appropriate for gestational age with no skin or mucosal lesions or other apparent complications.
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