刺激电极的临界半径与心脏激活有关

E. Cocherová, J. Púc̆ik, P. Kubinec, P. Kupec, O. Ondrácek
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引用次数: 0

摘要

本文探讨了刺激电流阈值与刺激电极半径及其他心脏组织参数的关系。在心脏壁的均质板模型上评估了这种依赖性,并通过改进的FitzHugh-Nagumo模型确定了局部膜特性。模拟结果表明,刺激电流密度阈值与组织电导率相关的扩散率和膜激发阈值成正比。它也与刺激电极半径成反比。在给定模型参数下,估计的刺激电极临界半径为0.8 mm,并与仿真结果进行了比较。半径较小的刺激电极在激发心脏组织兴奋方面是无效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The critical radius of stimulation electrode related to heart activation
This article examines the dependence of stimulation current threshold on stimulation electrode radius and other cardiac tissue parameters. The dependence was evaluated on a homogeneous slab model of the heart wall, with local membrane properties determined by modified FitzHugh-Nagumo model. Simulation results reveal that stimulation current density threshold depends proportionally on diffusivity related to tissue conductivity and on membrane excitation threshold. It is also inversely proportional to stimulation electrode radius. The critical radius of the stimulation electrode for the given model parameters estimated to be 0.8 mm was compared with simulation results. Stimulation electrodes with smaller radius are ineffective in eliciting excitation in the cardiac tissue.
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