Microfluidic analysis of micro needle array for drug delivery applications

In this paper, we design and analyze a mechanical bi-leaflet valve to replace the damaged valve using Nickel-Titanium (NiTi) a shape memory alloy created using COMSOL multiphysics software with 60-150 mmhg as input pressure to the valve is tested against the displacement and stress is noticed in the valve. There by loweringIn this paper, microneedles array based on out-of-plane for a transdermal drug delivery system was investigated structurally and microfluidically. There has been an upswing in studying the materials and production procedures for microneedles which promise nearly painless penetration through the skin. A single tip of a microneedle was constructed and the tip was developed into 36 microneedles array. The analysis and simulation of the microneedle were carried out using COMSOL Analysis (FEM) as a tool to determine the effect of the axial and transverse loads induced during the insertion of the microneedle into the skin and the results were presented. In order to examine the pressure distribution of fluid over a 36-microneedle array, a static analysis was performed. We acquired the 36 array of needles as a patch that it completed the purpose of enabling the fluid reaches the specified location. It also prevents any potential discomfort during the implantation. the chance of backflow of blood. The displacement and stress distribution parameters were analyzed. For the applied pressure 140mmhg which is equivalent to the normal pressure. From the obtained results, it is clear that the designed actuator is highly optimized structure to prevent the patient from heart attack.