印度尼西亚蜂蜜对糖尿病足溃疡愈合过程的有效性:观察性案例研究

Anita Sukarno, Nur Hidayah, M. Musdalifah
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引用次数: 2

摘要

背景:糖尿病足溃疡是全球范围内进行性发展的常见糖尿病并发症。麦卢卡蜂蜜在伤口愈合过程中的功效目前已被大量报道。现代调味品和麦卢卡蜂蜜可能负担不起,也不符合成本效益,因为这些调味品最初不是在印度尼西亚生产的。此外,对印尼蜂蜜发表的研究仍然缺乏。因此,我们进行了这项研究,以调查印度尼西亚蜂蜜在糖尿病足溃疡愈合过程中的有效性。方法:本研究设计为观察性病例研究。本研究于2014年3月至6月在印度尼西亚望加锡市Griya afia家庭护理和ETN中心对患有糖尿病足溃疡的2型糖尿病患者进行了研究。采用贝茨伤口评估工具(Bates Wound Assessment Tool, BWAT)对糖尿病足溃疡愈合过程中创面大小、深度、边缘、破坏程度、坏死组织类型、坏死量、肉芽、上皮、渗出物类型和数量、周围皮肤颜色、水肿和硬结进行评分。适当地进行描述性检验、独立t检验、方差分析(ANOVA)和Wilcoxon符号秩检验。结果:共纳入10例2型糖尿病合并糖尿病足溃疡患者。与创面愈合过程相关的因素为糖尿病治疗(t= 2.44, p= 0.041)和初次包扎(t= -2.76, p= 0.025)。蜂蜜初敷对创面缩小(p= 0.043)、改善坏死组织类型(p= 0.041)、减少坏死组织数量(p= 0.042)、增加肉芽(p= 0.038)和上皮(p= 0.042)的影响。相反,现代敷料的作用是改善坏死组织类型(p= 0.046)和增加肉芽(p= 0.042)。结论:印尼蜂蜜有利于糖尿病足溃疡的愈合。建议:因此,研究结果表明,蜂蜜应该被认为是糖尿病足溃疡的另一种经济有效且有益的伤口敷料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EFFECTIVITY OF INDONESIAN HONEY ON DIABETIC FOOT ULCERS HEALING PROCESS: OBSERVATIONAL CASE STUDY
Background: Diabetic foot ulcers were common diabetes complication that progressively growth globally. The effectivity of Manuka honey in wound healing process was huge published currently. Modern dressing and Manuka honey may not affordable and cost effective since these dressings were not produced originally in Indonesia. In addition, the published study of Indonesian honey is still lack. Therefore, we conducted this study to investigate the effectivity of Indonesian honey in diabetic foot ulcers healing process. Method: This study design was observational case study. This study was conducted among type 2 diabetes with diabetic foot ulcers in Griya Afiat Homecare and ETN Center in Makassar City, Indonesia from March to June 2014. The Bates Wound Assessment Tool (BWAT) were used to collect the score of diabetic foot ulcer healing process regarding wound size, depth, edges, undermining, necrotic tissue type, necrotic amount, granulation, epithelization, exudate type and amount, surrounding skin color, edema and induration. Descriptive, Independent t-test, Analysis of Variance (ANOVA) and Wilcoxon signed rank test were conducted appropriately. Results: In total, 10 type 2 diabetes patients with diabetic foot ulcers were participated. The factors associated with wound healing process were diabetes treatment (t= 2.44, p= 0.041) and primary dressing (t= -2.76, p= 0.025). The effect of honey primary dressing was in reducing wound size (p= 0.043), improving necrotic tissue type (p= 0.041), reducing necrotic tissue amount (p= 0.042), increasing granulation (p= 0.038) and epithelization (p= 0.042). In the counterpart, the effect of modern dressing was in improving necrotic tissue type (p= 0.046) and increasing granulation (p= 0.042). Conclusion: Indonesian honey is beneficial on diabetic foot ulcers healing process. Recommendation: Therefore, findings suggest that honey should be considered as the alternative, cost effective and beneficial wound dressing on the diabetic foot ulcers.
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