胃癌流行病学:塔那那利佛大学医院中心的经验胃癌流行病学:塔那那利佛大学医院中心的经验

Toky Rakotoarivo, M. Razakanaivo, M. J. Rakotonaivo, Mioramamy Jessica Ratsimanampoaka, F. Rafaramino, F. Rasoaherinomenjanahary, L. Samison
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摘要

背景:胃癌的治疗是低收入国家面临的主要挑战。本研究的目的是描述塔那那利佛Joseph Ravoahangy Andrianavalona大学医院中心内脏外科病房胃癌的流行病学、临床和治疗方面的情况。材料与方法:本研究为描述性回顾性研究,研究时间为2010年1月至2016年12月。所有18岁以上经组织学证实的胃癌住院患者均纳入研究。分析流行病学、临床及治疗方法。结果评估不是本研究的主题。结果:68例确诊为胃癌。平均年龄为56.5岁。幽门螺杆菌感染是主要危险因素。消化道出血和慢性胃脘痛是最明显的临床表现。溃疡和增生的胃损伤是最常见的,优先位于幽门窦(n = 38)。手术治愈24例,缓解13例。4名患者接受了初步化疗,27名患者在确诊后拒绝继续治疗。乳头状腺癌是最常见的组织学类型(n = 32)。结论:本院胃癌发现较晚。目前,所有年龄组都面临危险因素。内镜筛查和根除幽门螺杆菌感染应该是强制性的。在管理中,多学科是必不可少的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EPIDEMIOLOGIE DU CANCER GASTRIQUE : EXPERIENCE D’UN CENTRE HOSPITALIER UNIVERSITAIRE D’ANTANANARIVO EPIDEMIOLOGY OF GASTRIC CANCER: EXPERIENCE OF AN UNIVERSITY HOSPITAL CENTER IN ANTANANARIVO
Background: The management of gastric cancer is a major challenge in low-income countries. The aim of this study was to describe the epidemiological, clinical and therapeutic aspects of gastric cancer in the Visceral Surgery ward of the Centre Hospitalier Universitaire Joseph Ravoahangy Andrianavalona  in Antananarivo. Materials and Method: This was a descriptive retrospective study conducted from January 2010 to December 2016. All patients over 18 years of age hospitalized for gastric cancer with histological confirmation were included in the study. The epidemiological, clinical and therapeutic methods were analyzed. Outcome assessment will not be the subject of this study. Results: Gastric cancer was confirmed in 68 patients. The average age was 56.5. Helicobacter pylori infection was the main risk factor. Gastrointestinal  bleeding and chronic epigastric pain were the most revealing clinical manifestations. Ulcerous and exuberant gastric injuries were the most frequent, preferentially located in the pyloric antrum (n = 38). Surgery was curative in 24 patients, palliative in 13 patients. Four patients received primary chemotherapy and 27 refused to continue treatment when the diagnosis was announced. Papillary adenocarcinoma was the most common histological type (n = 32). Conclusion: gastric cancer is discovered at an advanced stage in our center. Currently, all age groups are exposed to risk factors. Endoscopic screening and eradication of Helicobacter Pylori infection should be mandatory. Multidisciplinarity is essential in the management.
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