基于集成的模糊与基于粒子群优化的加权聚类(Efpso-Wc)和基因本体的芯片基因表达

M. Thangamani, J. A. Ibrahim
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引用次数: 7

摘要

数据聚类被证明是一种有用的数据挖掘方法,用于查找数据集中存在的匹配对象集。管理海量数据的可伸缩性、对固有异常数据的可靠性和聚类结果的有效性是任何数据聚类技术中的重要问题。为了解决这些问题,本研究引入了一种基于集成的模糊与粒子群优化的加权聚类(EFPSO-WC)技术,该技术在各个阶段广泛并行分布。本文利用基因本体(Gene Ontology, GO)建立基因间的生物相关性,并利用粒子群算法对其进行优化。在新引入的工作中,Ensemble将一组对象的模糊聚类、模糊加权聚类(FWC)和FPSO-WC获得的不同聚类结果集成为一个集成的分类聚类,通常称为和谐解。与单一聚类技术相比,这种聚类可以生成更可靠、更均衡的聚类结果,可以在严格的条件下进行分布式计算,也可以实现信息共享。此外,将新引入的EFPSO-WC方法在可扩展性和可靠性方面的有效性与最近开展的同类研究进行了比较。在所有陈述的评估分析中,所提出的技术比最近在相同数据集上进行的工作表现更好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ensemble Based Fuzzy with Particle Swarm Optimization Based Weighted Clustering (Efpso-Wc) and Gene Ontology for Microarray Gene Expression
Data clustering proves to be a useful data mining approach for finding the sets of matching objects existing in the dataset. Scalability to manage massive volumes, reliability towards inherent outlier data and validity of clustering outcomes include the important issues in any data clustering technique. With the aim of addressing these problems, an Ensemble based fuzzy with Particle Swarm Optimization based Weighted Clustering (EFPSO-WC) technique that is extensively parallel and distributed in each stage, is introduced in this research work. Here Gene Ontology (GO) can be utilized for establishing the weight owing to the biological relevance exhibited by genes and its optimization is performed employing PSO. In the newly introduced work, Ensemble integrates different clustering outcomes achieved from fuzzy clustering, Fuzzy Weighted Clustering (FWC) and FPSO-WC of a group of objects into one integrated assorted clustering, frequently known as the harmony solution. This clustering can be utilized for the generation of more reliable and balanced clustering outcomes in comparison with a single clustering technique, carry out distributed computing under strict conditions or sharing information. In addition, the effectiveness of the newly introduced EFPSO-WC approach in terms of scalability and reliability was the compared with recently performed researches on the same subject. In all of the stated assessment analysis, the proposed technique performed better than the works carried out recently on the same datasets.
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