{"title":"加重度洛西汀对氯氮平治疗难治性精神分裂症阴性症状的影响","authors":"Ritvij M Satodiya","doi":"10.52803/421IRN","DOIUrl":null,"url":null,"abstract":"The negative symptoms of schizophrenia have always been a challenge in treatment. The intensity and chronicity of these symptoms has direct impact on the life quality and treatment response. Current psychopharmacological agents have not offered a satisfactory result in addressing the negative symptoms of schizophrenia. The clinicians struggle with the approaches that can be utilized to target the negative symptoms of schizophrenia as no well-defined evidence exist. We present a case of treatment resistant schizophrenia with negative symptoms that responded well with augmentation of Duloxetine to Clozapine treatment.","PeriodicalId":162316,"journal":{"name":"Addiction And Therapies","volume":"66 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effects of duloxetine augmentation on clozapine in the treatment of negative symptoms in treatment resistant schizophrenia\",\"authors\":\"Ritvij M Satodiya\",\"doi\":\"10.52803/421IRN\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The negative symptoms of schizophrenia have always been a challenge in treatment. The intensity and chronicity of these symptoms has direct impact on the life quality and treatment response. Current psychopharmacological agents have not offered a satisfactory result in addressing the negative symptoms of schizophrenia. The clinicians struggle with the approaches that can be utilized to target the negative symptoms of schizophrenia as no well-defined evidence exist. We present a case of treatment resistant schizophrenia with negative symptoms that responded well with augmentation of Duloxetine to Clozapine treatment.\",\"PeriodicalId\":162316,\"journal\":{\"name\":\"Addiction And Therapies\",\"volume\":\"66 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-04-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Addiction And Therapies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52803/421IRN\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Addiction And Therapies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52803/421IRN","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effects of duloxetine augmentation on clozapine in the treatment of negative symptoms in treatment resistant schizophrenia
The negative symptoms of schizophrenia have always been a challenge in treatment. The intensity and chronicity of these symptoms has direct impact on the life quality and treatment response. Current psychopharmacological agents have not offered a satisfactory result in addressing the negative symptoms of schizophrenia. The clinicians struggle with the approaches that can be utilized to target the negative symptoms of schizophrenia as no well-defined evidence exist. We present a case of treatment resistant schizophrenia with negative symptoms that responded well with augmentation of Duloxetine to Clozapine treatment.