酵母基因组复制后基因缺失的模式

2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05) Pub Date : 2005-08-08 DOI:10.1109/CSBW.2005.104

J. Byrnes, Wen-Hsiung Li

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引用次数: 2

摘要

全基因组复制(WGD)之后是大量重复缺失，重组基因邻接。我们比较了酵母WGD后的缺失模式和邻接重组与模拟。我们发现，在随机重复删除模型下，在旁系染色体之间的删除事件比预期的更频繁。

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Patterns of gene deletion following genome duplication in yeast

Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following WGD in yeast with simulations. We find that deletion events alternate between paralogous chromosomes more often than expected under a random duplicate deletion model.

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2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05)

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