离体大鼠心脏中的钙悖论——地尔硫卓的作用。

Physiologia Bohemoslovaca Pub Date : 1990-01-01

T Ravingerová, A Ziegelhöffer, N Tribulová, J Slezák, V Trégerová

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摘要

钙进入阻滞剂的保护作用可以在钙悖论模型上进行有利的研究，特别是在血流动力学和生化参数的保存以及心肌结构的基础上(Meno et al. 1984)。在这项研究中，我们的目的是测试最近开发的捷克斯洛伐克药物地尔硫卓(LACHEMA)在Ca2+悖论条件下的保护作用。

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Calcium paradox in the isolated rat-heart--the effects of diltiazem.

The protective effect of calcium entry blockers can be studied advantageously on the model of the calcium paradox, particularly on the basis of the preservation of haemodynamic and biochemical parameters as well as on the structure of the myocardium (Meno et al. 1984). Our aim in this study was to test the protective effect of the recently developed Czechoslovak drug diltiazem (LACHEMA) under conditions of the Ca2+ paradox.

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Physiologia Bohemoslovaca

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