H. Shin, H. W. Jang, Keun-Sook Kim, Ji In Lee, J. Park, S. Kim, Y. Min, Myung-Shik Lee, Moon-Kyu Lee, K. Kim, J. Chung
{"title":"寻找影响人甲状腺髓样癌细胞增殖的物质","authors":"H. Shin, H. W. Jang, Keun-Sook Kim, Ji In Lee, J. Park, S. Kim, Y. Min, Myung-Shik Lee, Moon-Kyu Lee, K. Kim, J. Chung","doi":"10.3803/JKES.2009.24.2.93","DOIUrl":null,"url":null,"abstract":"1 , ABSTRACT Background: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation were recently reported. Presently, we evaluated the influence of dexamethasone, somatostatin, progesterone, estradiol-17-beta, forskolin and gastrin on MTC cell proliferation and calcitonin secretion. Methods: Genomic DNA was extracted and sequenced from untreated thyroid TT cells and cells treated with 10","PeriodicalId":119859,"journal":{"name":"Journal of Korean Endocrine Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation\",\"authors\":\"H. Shin, H. W. Jang, Keun-Sook Kim, Ji In Lee, J. Park, S. Kim, Y. Min, Myung-Shik Lee, Moon-Kyu Lee, K. Kim, J. Chung\",\"doi\":\"10.3803/JKES.2009.24.2.93\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"1 , ABSTRACT Background: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation were recently reported. Presently, we evaluated the influence of dexamethasone, somatostatin, progesterone, estradiol-17-beta, forskolin and gastrin on MTC cell proliferation and calcitonin secretion. Methods: Genomic DNA was extracted and sequenced from untreated thyroid TT cells and cells treated with 10\",\"PeriodicalId\":119859,\"journal\":{\"name\":\"Journal of Korean Endocrine Society\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Korean Endocrine Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3803/JKES.2009.24.2.93\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Korean Endocrine Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3803/JKES.2009.24.2.93","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation
1 , ABSTRACT Background: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation were recently reported. Presently, we evaluated the influence of dexamethasone, somatostatin, progesterone, estradiol-17-beta, forskolin and gastrin on MTC cell proliferation and calcitonin secretion. Methods: Genomic DNA was extracted and sequenced from untreated thyroid TT cells and cells treated with 10