利用弹性网和赫斯特指数发现遗传多样性的生物信息学工具

L. M. Ferreira, T. Sáfadi, T. Setotaw, J. L. Ferreira
{"title":"利用弹性网和赫斯特指数发现遗传多样性的生物信息学工具","authors":"L. M. Ferreira, T. Sáfadi, T. Setotaw, J. L. Ferreira","doi":"10.5772/INTECHOPEN.82755","DOIUrl":null,"url":null,"abstract":"The genome era allowed us to evaluate different aspects on genetic variation, with a precise manner followed by a valuable tip to guide the improvement of knowledge and direct to upgrade to human life. In order to scrutinize these treasured resources, some bioinformatics tools permit us a deep exploration of these data. Among them, we show the importance of the discrete non-decimated wavelet transform (NDWT). The wavelets have a better ability to capture hidden components of biological data and an efficient link between biological systems and the mathematical objects used to describe them. The decomposition of signals/ sequences at different levels of resolution allows obtaining distinct characteristics in each level. The analysis using technique of wavelets has been growing increasingly in the study of genomes. One of the great advantages associated to this method corresponds to the computational gain, that is, the analyses are processed almost in real time. The applicability is in several areas of science, such as physics, mathematics, engineering, and genetics, among others. In this context, we believe that using R software and applied NDWT coupled with elastic net domains and Hurst exponent will be of valuable guideline to researchers of genetics in the investigation of the genetic variability.","PeriodicalId":301810,"journal":{"name":"Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations","volume":"25 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Bioinformatics Tools for Discovery of Genetic Diversity by Means of Elastic Net and Hurst Exponent\",\"authors\":\"L. M. Ferreira, T. Sáfadi, T. Setotaw, J. L. Ferreira\",\"doi\":\"10.5772/INTECHOPEN.82755\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The genome era allowed us to evaluate different aspects on genetic variation, with a precise manner followed by a valuable tip to guide the improvement of knowledge and direct to upgrade to human life. In order to scrutinize these treasured resources, some bioinformatics tools permit us a deep exploration of these data. Among them, we show the importance of the discrete non-decimated wavelet transform (NDWT). The wavelets have a better ability to capture hidden components of biological data and an efficient link between biological systems and the mathematical objects used to describe them. The decomposition of signals/ sequences at different levels of resolution allows obtaining distinct characteristics in each level. The analysis using technique of wavelets has been growing increasingly in the study of genomes. One of the great advantages associated to this method corresponds to the computational gain, that is, the analyses are processed almost in real time. The applicability is in several areas of science, such as physics, mathematics, engineering, and genetics, among others. In this context, we believe that using R software and applied NDWT coupled with elastic net domains and Hurst exponent will be of valuable guideline to researchers of genetics in the investigation of the genetic variability.\",\"PeriodicalId\":301810,\"journal\":{\"name\":\"Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations\",\"volume\":\"25 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.82755\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.82755","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

基因组时代使我们能够评估基因变异的不同方面,以精确的方式获得有价值的提示,指导知识的改进和人类生活的直接升级。为了仔细研究这些宝贵的资源,一些生物信息学工具允许我们对这些数据进行深入的探索。其中,我们证明了离散非抽取小波变换(NDWT)的重要性。小波有更好的能力捕捉生物数据的隐藏成分,并在生物系统和用于描述它们的数学对象之间建立有效的联系。在不同分辨率水平上对信号/序列进行分解,可以在每个水平上获得不同的特征。小波分析技术在基因组研究中得到越来越多的应用。该方法的一大优点在于计算增益,即分析几乎是实时处理的。它的适用性在许多科学领域,如物理、数学、工程和遗传学等。在此背景下,我们认为利用R软件,将NDWT与弹性网域和Hurst指数相结合,将为遗传学研究人员研究遗传变异提供有价值的指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Bioinformatics Tools for Discovery of Genetic Diversity by Means of Elastic Net and Hurst Exponent
The genome era allowed us to evaluate different aspects on genetic variation, with a precise manner followed by a valuable tip to guide the improvement of knowledge and direct to upgrade to human life. In order to scrutinize these treasured resources, some bioinformatics tools permit us a deep exploration of these data. Among them, we show the importance of the discrete non-decimated wavelet transform (NDWT). The wavelets have a better ability to capture hidden components of biological data and an efficient link between biological systems and the mathematical objects used to describe them. The decomposition of signals/ sequences at different levels of resolution allows obtaining distinct characteristics in each level. The analysis using technique of wavelets has been growing increasingly in the study of genomes. One of the great advantages associated to this method corresponds to the computational gain, that is, the analyses are processed almost in real time. The applicability is in several areas of science, such as physics, mathematics, engineering, and genetics, among others. In this context, we believe that using R software and applied NDWT coupled with elastic net domains and Hurst exponent will be of valuable guideline to researchers of genetics in the investigation of the genetic variability.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信