[急性精神病综合征和喹诺酮类药物]。

J F Defoin, T Debonne, M O Rambourg, J Seraphin, M Buffet, M Jaussaud, R Bertault, R Fay, B Digeon
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引用次数: 0

摘要

报告氟甲喹中毒1例;一名13岁的女孩因精神综合症入院。3 h后出现癫痫发作、昏迷、代谢紊乱。怀疑有传染病、脑病或糖尿病,但未确诊。对症治疗12小时后,患者临床情况好转,出院。当时在她的卧室里发现了一块药片,光谱分析结果显示氟甲喹呈阳性。本病例报告与以往的观察结果一致,并证实了喹诺酮类药物的治疗指数很小,并且绝对有必要仔细评估精神病学诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Acute psychiatric syndrome and quinolones].

A case of Flumequine poisoning is described; a 13-year-old girl was admitted for a psychiatric syndrome. 3 hours after, seizures, coma, and metabolic disorders were observed. Infectious, encephalitic or diabetic diseases were suspected, but not confirmed. After 12 hours of a symptomatic treatment, the clinical status improved and the patient was discharged. At that time a tablet was found in her bedroom and a mas spectrographic analysis was positive for Flumequine. This case report is in agreement with previous observations and confirms the small therapeutic index of quinolone, and the absolute necessity to assess carefully a psychiatric diagnosis.

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