{"title":"线性IgA大疱性皮肤病(LABD):一种新发现的疾病。","authors":"A Gakiopoulou, A Sklavounou, N Mortakis","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In previous years linear IgA bullous dermatosis (LABD) of the adults has caused considerable discussion as to its classification. Some investigators considered LABD to be a subgroup of pemphigoid and others regarded it as being more closely related to dermatitis herpetiformis. However a growing body of evidence points to LABD as a distinct disease entity which is characterized by IgA staining along the basement membrane zone in a linear pattern (Chorzelski et al 1979). In this paper a review of this newly recognized entity is attempted, based on the reports from the literature. The clinico-pathologic and immunologic features of LABD are analyzed and discussed and emphasis is given to the problem of differential diagnosis with other bullous dermatoses.</p>","PeriodicalId":77643,"journal":{"name":"To Helleniko periodiko gia stomatike & gnathoprosopike cheirourgike","volume":"5 2","pages":"81-8"},"PeriodicalIF":0.0000,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Linear IgA bullous dermatosis (LABD): a recently recognized entity].\",\"authors\":\"A Gakiopoulou, A Sklavounou, N Mortakis\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In previous years linear IgA bullous dermatosis (LABD) of the adults has caused considerable discussion as to its classification. Some investigators considered LABD to be a subgroup of pemphigoid and others regarded it as being more closely related to dermatitis herpetiformis. However a growing body of evidence points to LABD as a distinct disease entity which is characterized by IgA staining along the basement membrane zone in a linear pattern (Chorzelski et al 1979). In this paper a review of this newly recognized entity is attempted, based on the reports from the literature. The clinico-pathologic and immunologic features of LABD are analyzed and discussed and emphasis is given to the problem of differential diagnosis with other bullous dermatoses.</p>\",\"PeriodicalId\":77643,\"journal\":{\"name\":\"To Helleniko periodiko gia stomatike & gnathoprosopike cheirourgike\",\"volume\":\"5 2\",\"pages\":\"81-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"To Helleniko periodiko gia stomatike & gnathoprosopike cheirourgike\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"To Helleniko periodiko gia stomatike & gnathoprosopike cheirourgike","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
近年来,成人线性IgA大疱性皮肤病(LABD)的分类引起了广泛的讨论。一些研究者认为LABD是类天疱疮的一个亚群,另一些研究者认为LABD与疱疹样皮炎的关系更密切。然而,越来越多的证据表明,LABD是一种独特的疾病实体,其特征是IgA沿基底膜区呈线性染色(Chorzelski et al . 1979)。在本文中,回顾了这一新认识的实体,试图从文献的报告为基础。分析和讨论了LABD的临床病理和免疫学特征,并重点讨论了与其他大疱性皮肤病的鉴别诊断问题。
[Linear IgA bullous dermatosis (LABD): a recently recognized entity].
In previous years linear IgA bullous dermatosis (LABD) of the adults has caused considerable discussion as to its classification. Some investigators considered LABD to be a subgroup of pemphigoid and others regarded it as being more closely related to dermatitis herpetiformis. However a growing body of evidence points to LABD as a distinct disease entity which is characterized by IgA staining along the basement membrane zone in a linear pattern (Chorzelski et al 1979). In this paper a review of this newly recognized entity is attempted, based on the reports from the literature. The clinico-pathologic and immunologic features of LABD are analyzed and discussed and emphasis is given to the problem of differential diagnosis with other bullous dermatoses.