M. Ramírez-Bonilla, C.I. Villeda-Sandoval, G. Romero-Vélez, A. Lisker-Cervantes, J.J. Cendejas-Gómez, B. González-Sánchez, D. Olvera-Posada, M. García-Sánchez, R.A. Castillejos-Molina, M. Sotomayor-de Zavaleta
{"title":"射精对前列腺特异性抗原水平没有影响","authors":"M. Ramírez-Bonilla, C.I. Villeda-Sandoval, G. Romero-Vélez, A. Lisker-Cervantes, J.J. Cendejas-Gómez, B. González-Sánchez, D. Olvera-Posada, M. García-Sánchez, R.A. Castillejos-Molina, M. Sotomayor-de Zavaleta","doi":"10.1016/j.uromx.2015.07.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Prostate-specific antigen (PSA) is a tumor marker used in the diagnosis of prostate cancer; it is organ-specific but it is not disease-specific. The effect of ejaculation on PSA concentration is controversial.</p></div><div><h3>Aim</h3><p>To evaluate the impact of PSA values after ejaculation on biopsy indication in a screened population.</p></div><div><h3>Methods</h3><p>Baseline PSA was measured in 100 patients that had abstained from sexual activity for at least 7<!--> <!-->days. A second measurement was carried out 48<!--> <!-->h after ejaculation. The numerical differences were compared using the Student's t test. The McNemar's test was used to analyze pre and post-ejaculation values and clinical significance was defined as a PSA value above a pre-established limit for biopsy indication.</p></div><div><h3>Results</h3><p>Mean age of the patients was 52.7<!--> <!-->±<!--> <!-->8.6<!--> <!-->years. The mean baseline PSA was 1.39<!--> <!-->±<!--> <!-->1.43<!--> <!-->ng/mL and after ejaculation was 1.48<!--> <!-->±<!--> <!-->1.51<!--> <!-->ng/mL (<em>P</em> <!-->=<!--> <!-->.54). Two patients had PSA values that increased sufficiently for biopsy indication, using a parameter of 4<!--> <!-->ng/mL after ejaculation. The McNemar's test showed no statistically significant differences (<em>P</em> <!-->=<!--> <!-->.500).</p></div><div><h3>Conclusions</h3><p>There was no statistically significant difference in PSA after ejaculation and this change had no clinical relevance.</p></div>","PeriodicalId":34909,"journal":{"name":"Revista mexicana de urologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uromx.2015.07.004","citationCount":"0","resultStr":"{\"title\":\"La eyaculación no tiene impacto en los niveles de antígeno prostático específico\",\"authors\":\"M. Ramírez-Bonilla, C.I. Villeda-Sandoval, G. Romero-Vélez, A. Lisker-Cervantes, J.J. Cendejas-Gómez, B. González-Sánchez, D. Olvera-Posada, M. García-Sánchez, R.A. Castillejos-Molina, M. Sotomayor-de Zavaleta\",\"doi\":\"10.1016/j.uromx.2015.07.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Prostate-specific antigen (PSA) is a tumor marker used in the diagnosis of prostate cancer; it is organ-specific but it is not disease-specific. The effect of ejaculation on PSA concentration is controversial.</p></div><div><h3>Aim</h3><p>To evaluate the impact of PSA values after ejaculation on biopsy indication in a screened population.</p></div><div><h3>Methods</h3><p>Baseline PSA was measured in 100 patients that had abstained from sexual activity for at least 7<!--> <!-->days. A second measurement was carried out 48<!--> <!-->h after ejaculation. The numerical differences were compared using the Student's t test. The McNemar's test was used to analyze pre and post-ejaculation values and clinical significance was defined as a PSA value above a pre-established limit for biopsy indication.</p></div><div><h3>Results</h3><p>Mean age of the patients was 52.7<!--> <!-->±<!--> <!-->8.6<!--> <!-->years. The mean baseline PSA was 1.39<!--> <!-->±<!--> <!-->1.43<!--> <!-->ng/mL and after ejaculation was 1.48<!--> <!-->±<!--> <!-->1.51<!--> <!-->ng/mL (<em>P</em> <!-->=<!--> <!-->.54). Two patients had PSA values that increased sufficiently for biopsy indication, using a parameter of 4<!--> <!-->ng/mL after ejaculation. The McNemar's test showed no statistically significant differences (<em>P</em> <!-->=<!--> <!-->.500).</p></div><div><h3>Conclusions</h3><p>There was no statistically significant difference in PSA after ejaculation and this change had no clinical relevance.</p></div>\",\"PeriodicalId\":34909,\"journal\":{\"name\":\"Revista mexicana de urologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.uromx.2015.07.004\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista mexicana de urologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2007408515001032\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista mexicana de urologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2007408515001032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
La eyaculación no tiene impacto en los niveles de antígeno prostático específico
Background
Prostate-specific antigen (PSA) is a tumor marker used in the diagnosis of prostate cancer; it is organ-specific but it is not disease-specific. The effect of ejaculation on PSA concentration is controversial.
Aim
To evaluate the impact of PSA values after ejaculation on biopsy indication in a screened population.
Methods
Baseline PSA was measured in 100 patients that had abstained from sexual activity for at least 7 days. A second measurement was carried out 48 h after ejaculation. The numerical differences were compared using the Student's t test. The McNemar's test was used to analyze pre and post-ejaculation values and clinical significance was defined as a PSA value above a pre-established limit for biopsy indication.
Results
Mean age of the patients was 52.7 ± 8.6 years. The mean baseline PSA was 1.39 ± 1.43 ng/mL and after ejaculation was 1.48 ± 1.51 ng/mL (P = .54). Two patients had PSA values that increased sufficiently for biopsy indication, using a parameter of 4 ng/mL after ejaculation. The McNemar's test showed no statistically significant differences (P = .500).
Conclusions
There was no statistically significant difference in PSA after ejaculation and this change had no clinical relevance.
期刊介绍：
Revista Mexicana de Urología (RMU) [Mexican Journal of Urology] (ISSN: 0185-4542 / ISSN electronic: 2007-4085) is bimonthly publication that disseminates research by academicians and professionals of the international medical community interested in urological subjects, in the format of original articles, clinical cases, review articles brief communications and letters to the editor. Owing to its nature, it is publication with international scope that disseminates contributions in Spanish and English that are rigorously reviewed by peers under the double blind modality. Neither journalistic documents nor those that lack rigorous medical or scientific support are suitable for publication.
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