指甲花的抗结核活性

V.K. Sharma
{"title":"指甲花的抗结核活性","authors":"V.K. Sharma","doi":"10.1016/0041-3879(90)90044-9","DOIUrl":null,"url":null,"abstract":"<div><p>The tuberculostatic activity of the herb henna (<em>Lawsonia inermis</em> Linn.) was tested <em>in vitro</em> and <em>in vivo</em>. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of <em>Mycobacterium tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv was inhibited by 6 μg/ml of the herb. <em>In vivo</em> studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with <em>M. tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv.</p></div>","PeriodicalId":23472,"journal":{"name":"Tubercle","volume":"71 4","pages":"Pages 293-295"},"PeriodicalIF":0.0000,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0041-3879(90)90044-9","citationCount":"86","resultStr":"{\"title\":\"Tuberculostatic activity of henna (Lawsonia inermis Linn.)\",\"authors\":\"V.K. Sharma\",\"doi\":\"10.1016/0041-3879(90)90044-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The tuberculostatic activity of the herb henna (<em>Lawsonia inermis</em> Linn.) was tested <em>in vitro</em> and <em>in vivo</em>. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of <em>Mycobacterium tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv was inhibited by 6 μg/ml of the herb. <em>In vivo</em> studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with <em>M. tuberculosis</em> H<sub>3</sub><sub>7</sub>Rv.</p></div>\",\"PeriodicalId\":23472,\"journal\":{\"name\":\"Tubercle\",\"volume\":\"71 4\",\"pages\":\"Pages 293-295\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0041-3879(90)90044-9\",\"citationCount\":\"86\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tubercle\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0041387990900449\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tubercle","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0041387990900449","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 86

摘要

本文对中药指甲花(Lawsonia inermis Linn.)的体外和体内抑菌活性进行了研究。在Lowenstein Jensen培养基上,6 μg/ml的中草药能抑制痰液结核杆菌和结核分枝杆菌H37Rv的生长。对豚鼠和小鼠的体内研究表明,剂量为5 mg/kg体重的中药可显著缓解结核分枝杆菌H37Rv感染后的实验性结核病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tuberculostatic activity of henna (Lawsonia inermis Linn.)

The tuberculostatic activity of the herb henna (Lawsonia inermis Linn.) was tested in vitro and in vivo. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of Mycobacterium tuberculosis H37Rv was inhibited by 6 μg/ml of the herb. In vivo studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with M. tuberculosis H37Rv.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信