癌症治疗的进展

Bilge Bicak, Serda Kecel Gunduz, Aysen E. Ozel
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引用次数: 1

摘要

靶向给药是提高药物疗效和减少毒副作用的一种非常方便的癌症治疗方法。纳米给药系统具有独特的物理、化学、机械和光学特性。纳米颗粒具有较大的表面积和功能基团,可以结合治疗药物,有利于纳米颗粒制剂的药物分布,并可以提供新的特性。它们还使个人肿瘤学能够进行诊断和治疗,这适合癌症患者的个人分子谱结构。将肿瘤靶向活性物质附着在纳米颗粒上,将负载活性物质的纳米颗粒靶向到肿瘤区域;这些纳米颗粒具有很强的结合倾向和特异性,可以靶向肿瘤抗原或血管。除了传统的癌症治疗领域的化疗和放疗方法外,本章旨在提供靶向药物递送系统的信息,以靶向癌细胞而不损害正常组织。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advancements in Cancer Therapeutics
Targeted drug delivery in cancer treatment is a very convenient method for increasing the effectiveness of drugs and reducing their toxic side effects. Nano drug delivery systems have unique physical, chemical, mechanical, and optical properties. Nanoparticles, which have large surface areas and functional groups for the binding of therapeutic agents, benefit the drug distribution with nanoparticle formulations and can provide new features. They also enable personal oncology for diagnosis and treatment, which is appropriate for the personal molecular profile structures of cancer patients. The tumor-targeted active substances are attached to nanoparticles and the active substance loaded nanoparticles are targeted to the tumor area; these nanoparticles can be used with a high tendency to bind and specificity, to target tumor antigens or vessels. This chapter, besides traditional chemotherapy and radiotherapy methods in the field of cancer treatment, is aimed to give information about targeted drug delivery systems for cancer cell targeting without damaging normal tissues.
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